Scientists at Plovdiv Medical University identify best materials for border molding in complete dentures fabrication

Edentulous jaw is a condition where either the upper (maxilla) or the lower (mandible) jaw is missing all teeth. In medical practice, it could be treated by placement of a complete denture. 

Previous research has already pointed that the application of a border molding procedure (or functional shaping) results in significantly fewer cases of pressure ulcers (decubitus) and soft tissues deformations, hence increased retention and stability of the prosthesis, both at rest and in function. Since there are many factors that affect the optimal treatment, such as anatomical structures (i.e. muscles, muscular and soft-tissue gripping) and the asymmetry between the left and right halves of upper and lower jaws, it is important that special care is taken to determine the depth, as well as the width of the tissue where the teeth would normally be nested (gingivobuccal sulcus). With border molding, it is possible to determine those, however, the accuracy of the impression would still largely depend on the materials used in the procedure.

Internal palatal surface (left) and side view (right) of the designed custom tray
Image: Dobromira Shopova, PhD

In their study, published in the open-access, peer-reviewed scholarly journal Folia Medica, Dr Dobromira Shopova and Prof. Diyan Slavchev at the Plovdiv Medical University (Bulgaria) sought to evaluate and determine the accuracy of two different groups of impression materials for border molding: thermoplastic and elastomers. They examined four different brands: Detaseal function (additive silicone for border molding), Sta-seal F (condensation silicone for border molding), GC Iso functional sticks (synthetic resin for border molding), Kerr Impression compound green sticks for border molding.

To perform their research, the team applied Dr Dobromira Shopova’s clinical method to measure negative pressure after border molding procedure, referred to as the vacuum measurement technique on edentulous upper jaw. They also assembled a special custom tray from a light-curing base plate with a palatal adapter. This was a 900, 7-millimetre metal adapter, which was fixed to the midline on the palatal slope. To create and measure the negative pressure, they used a combined pressure pump. The maximum value ​​was 3 bars for positive pressure and -1 bar for negative pressure.

Clinical setup of vacuum measurement after border molding of the custom tray of complete edentulous upper jaw
Image: Dobromira Shopova, PhD

Working protocol followed for all materials:

1. Apply the impression material along the edge of the individual tray;

2. Insert, position and perform Herbst functional tests;

3. Wait for the elasticity or hardening of the material;

4. Assemble the clinical unit for negative pressure measurement;

5. Measure the negative pressure that has been created between the custom tray and the prosthetic field, then record the result;

6. Release the individual impression tray from the patient’s mouth.

A statistically significant difference was observed between the two thermoplastic materials: the GC Iso functional sticks and the Impression compound green sticks. No statistically significant difference was observed between the other groups of materials. 

The measured mean negative pressure values ​​created between the prosthetic field and the custom tray showed close values ​​for each patient – with a difference of -0,05 to -0,1 bar. This showed that the anatomical features of the prosthetic field were of great importance.

In conclusion, quantitative measurement of negative pressure is entirely possible under clinical conditions. Thermoplastic materials for border molding are retained and formed only along the edge of the custom tray. However, silicone impression materials do not spread only on the edge of the custom tray, but also on the alveolar ridge, demonstrating their superior manipulative qualities and accuracy for the purposes of border molding.


Original source:


Shopova DA, Slavchev D (2020) Clinical Negative Pressure Measurement after Border Molding Procedure. Folia Medica 62(3): 578-584. https://doi.org/10.3897/folmed.62.e48464

Bulgarian Pharmaceutical Scientific Society’s journal moves to high-tech ARPHA platform

The established Pharmacia demonstrates a complete makeover in its new issue after signing with scientific publisher and technology provider Pensoft and its signature open-access platform

Launched by the Bulgarian Pharmaceutical Scientific Society in 1954, the open-access, peer-reviewed Pharmacia has been available online as full text since 2007. As of 2019, the journal moves to the fast-expanding portfolio of scholarly publisher and technology provider Pensoft. The journal’s 2019 inaugural issue and the first since the realisation of the new partnership is already live on the journal’s new website.

Homepage of Pharmacia‘s new website, https://pharmacia.pensoft.net

Thanks to the Pensoft’s signature open-access scholarly publishing platform ARPHA, Pharmacia demonstrates a complete makeover, including a modern and user-friendly interface in addition to a long list of high-tech perks, meant to ensure that published articles are easy to discover, access, cite and reuse by both humans and machines all over the world.

Furthermore, all users of the journal’s system: authors, editors and reviewers alike, are to greatly benefit of ARPHA’s integrated approach to the publication process. This means that once submitted each manuscript goes through the whole cycle: from review and copy/layout editing to publication, dissemination and archiving without leaving ARPHA’s collaboration-focused online environment.

One of the interesting features now available in Pharmacia is the article-level metrics available thanks to the partnership between ARPHA and the revolutionary discovery and analytics tools Dimensions and Altmetric. By searching through millions of research articles, grant applications, clinical trials, as well as policy documents, news stories, blogs and social media posts, they allow for each article’s references and citations in both the academic and the public sphere to be monitored in real time.

Continuing its tradition, the journal welcomes original research and review articles, preliminary and short communications (notes) on a wide range of topics within the pharmaceutical and related sciences. In addition, the journal also publishes conference reports, biographies and book reviews. Articles in Pharmacia are published in English and subjected to single-blind peer review.

Pharmacia‘s Editor-in-Chief Prof Plamen Peikov, comments:

“We have been looking forward to our collaboration with Pensoft and ARPHA, as it is certainly going to not only help modernise Pharmacia on the outside, but also make it more appealing to our authors and readers by building on the journal’s accessibility and global outreach. I believe that this nice step forward is already clearly evident in Pharmacia‘s latest issue.”

ARPHA’s and Pensoft’s founder and CEO Prof Lyubomir Penev says:

“I’m delighted to see this particular journal joining the Pensoft’s and ARPHA’s family,” says ARPHA’s and Pensoft’s founder and CEO Prof. Lyubomir Penev. “With our strong background in scholarly publishing, technology development and open science practices, I am certain that we are able to provide the right venue for a high-quality and enterprising journal like Pharmacia.”

What’s on in the new issue?

The creeping cinquefoil – a perennial plant from the Northern hemisphere – has its status as a traditional medicine for treating diarrhoea, haemorrhoids and bleeding gums confirmed in a collaborative ethnobotanical study by researchers at the Bulgarian Academy of Sciences and the Medical University of Sofia (Bulgaria). Further, the team, led by Irena Mincheva, seek to explore the suggested use of the plant against mastitis: a relatively common disease and a major cause for milk reduction in both people and dairy cows.

Another paper, authored by Dr Illya Podolsky and Sergiy Shtrygol from the National University of Pharmacy in Ukraine, adds new information about “the pharmacological nature” of a molecule already known as a promising antidepressant with a unique spectrum of additional properties. By conducting an experiment in rats, using the preferred Morris water maze assessment method, the scientists study the effects of Atristamine on spatial memory and learning.

Pharmacia‘s latest issue is available on the new website. Available in HTML, XML and PDF formats, the articles are easy to find, access, mine, reuse and cite by both humans and computers. Check out the issue at: https://pharmacia.pensoft.net/issue/1757/.

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Pharmacia is indexed by ScopusAltmetric, Biotechnobase, CAplusSM/Chemical Abstracts, CNKI, CrossRef, Dimensions, EBSCOhostEmbase, ExtraMED, Google Scholar, J-GateMEDLINE/PubMedMendeleyMicrosoft AcademicNaviga (Softweco)OpenAIREPascalReadCubeToxcenterUnpaywall.

About the Bulgarian Pharmaceutical Scientific Society:

The Bulgarian Pharmaceutical Scientific Society was registered in 2003 with the aim to organise national and international science forums, support education and publish academic literature. Its main objectives are to organise and encourage pharmacological research and support collaboration between pharmacology professionals and related organisations on both national and global level.

Russian-born Research Results in Pharmacology moves to high-tech journal platform ARPHA

The rebranded and refreshed journal is now published jointly by Belgorod National Research University and scholarly publisher and technology provider Pensoft

Since 2015, Belgorod National Research University‘s forward-thinking open-access and peer-reviewed scholarly journal Research Result: Pharmacology and Clinical Pharmacology has been filling an essential gap as a scholarly venue for publications dealing with long-year research outcomes in pharmacology and clinical pharmacology.

Now, having moved to the high-tech journal publishing platform ARPHA (abbreviation standing for Authoring, Reviewing, Publishing, Hosting and Archiving), the rebranded Research Results in Pharmacology demonstrates its refreshed format in its first issue jointly published with open-access scholarly publisher and technology provider Pensoft via the journal’s brand new website.

Continuing its tradition, the journal welcomes articles on various aspects within pharmacology, including papers devoted to molecular screening with the use of modern methods of proteomics, cellular technologies, results of experimental studies in modeling abnormalities in laboratory animals and clinical studies in the field of pharmacotherapy, pharmacokinetics, pharmacoepidemiology, personalised therapy, multicenter studies and evidence-based medicine. All articles are published in English, with versions in Russian published on Belgorod National Research University’s official website.

Apart from the evolution in its look-and-feel, thanks to the partnership with ARPHA, Research Results in Pharmacology now provides a long list of services at the disposal of all users – editors, reviewers, authors and readers alike, in order to ensure that articles are submitted, reviewed, published and disseminated rapidly and conveniently. To do this, the whole publication process takes place within ARPHA’s singular online environment.

Once published, each article is freely available in three formats (PDF, XML, HTML), enriched with a whole set of semantic enhancements, so that the articles, along with their data, are easy to discover, access and harvest by both humans and machines.

Amongst the high-tech perks greeting any online publication’s visitor are the article-level metrics available thanks to the partnership between ARPHA and the revolutionary discovery and analytics tools Dimensions and Altmetric. By searching through millions of research articles, grant applications, clinical trials, as well as policy documents, news stories, blogs and social media posts, they allow for each article’s references and citations in both the academic and the public sphere to be monitored in real time.

“I’m delighted to welcome this particular new member of the Pensoft’s and ARPHA’s family,” says ARPHA’s and Pensoft’s founder and CEO Prof. Lyubomir Penev. “With our strong background in scholarly publishing, technology development and open science practices, I am certain that we are able to provide the right venue for a brilliant and enterprising journal such as Research Results in Pharmacology.”

“I find our new partnership with ARPHA and Pensoft to be extremely advantageous for Research Results in Pharmacology, and this is already showing in our first issue since joining our efforts,” says Prof. Mikhail Pokrovsky, Editor-in-Chief at Research Results in Pharmacology. “I would like to especially thank Lyubomir and his team for fully understanding and meeting our needs, resulting in a wonderful professional collaboration, as well as friendship.”

Research Results in Pharmacology is the second Russian journal in ARPHA’s and Pensoft’s portfolios. Several new titles are expected to join them later this year.

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